Tuberculosis causes nearly 2 million people to die every year The medicine researches and develops progress
It is reported, tuberculosis causes about 2 million people to die every year, in infectious disease, its mortality is second only to AIDS (HIV/AIDS) . But 94% of the tuberculosis cases and 98% mortality take place in developing countries.
An article published of " lancet " thinks, global tuberculosis (TB) The medicine pipeline has made unprecedented progress, 10 kinds of drug candidate are at the clinical developing stage at present. The article author is a famous international panel of expert, are researched and developed Dr. Ma ZhenKun, chief scientist of alliance, to take the lead by the global tuberculosis medicine, it is a non-profit-making organization aiming at promoting the new tuberculosis medicine to research and develop that the global tuberculosis medicine researches and develops the alliance. As a part of serial articles of tuberculosis of magazine of " lancet ", enormous fund and other challenges that the article has also put emphasis on facing in order to save and is almost 2 million persons who dies of the tuberculosis each time.
In clinical medicine that develop in 10 kinds, 3 kinds are the tuberculosis medicine researched and developed common development of alliance and cooperative partner. Medicine of these clinical trials is basic components of the medicine therapeutic method of new tuberculosis of new generation, the therapeutic method of these medicines, through shortening the course of treatment, probably relieve global tuberculosis to bear greatly, the present course of treatment is 6-30 months. The model test that is carried on in an area of World Health Organization recently reveals, by 2050, new and improving tuberculosis medicine, vaccine and diagnostic method can reduce the global tuberculosis morbidity by 71%. In 2008, the example is more than 9 million that tuberculosis will have illness coming on newly.
> say: "10 years ago, did not basically research and develop the medicine curing tuberculosis, so this field had already made enormous progress now. However, must continue strengthening the global tuberculosis medicine pipeline, in order to guarantee we can offer the strong tool, help to dispel the disaster that tuberculosis brings to patient, family and global various countries. "
Dr. Ma ZhenKun thinks, obtains more, lasting fund and offers the tuberculosis treatment of future generation to patient, it is the medicine that researches and develops the greatest challenge that the pipeline faces. The borderless doctor's organization thinks, the ones that research and develop the essential tuberculosis medicine are short of fund 75% of Damien.
The general living beings of German horse infect immune department director Stephen Dr. Coifman (Dr.Stefan Kaufmann) of the research institute Say: "Though we are marching forward along the correct side, advance and face a lot of challenges in the way. Only everybody works as one man, the whole world supports together, could support the new tuberculosis medicine to research and develop, and lower the mortality of tuberculosis greatly and to economic influence. "
Therapeutic medicine sensitiveness and drug resistance disease need the association of many kinds of medicines. But until recently, treated in the tuberculosis prescription only a new medicine carries on the experimented. But initiated to many kinds of drug candidate recently " Key route (CPTR) of drug therapy of tuberculosis " The scheme, the purpose is to carry on several kinds of new medicines at the same time and make up and test. This may shorten and develop the time of treatment for method of innovative tuberculosis medicine greatly.
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